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For individuals using AOD-9604 as part of ongoing weight maintenance rather than active fat loss, lower doses (250-300 mcg) used several times weekly rather than daily may provide metabolic support while reducing cost and injection frequency
An intermediate level of 4 mg per week demonstrated enhanced weight loss compared to the starting dose while maintaining acceptable safety margins
10.1126/scitranslmed.aaf6397 Sci Transl Med
PLoS ONE 11:e0162318 Siegel R, Naishadham D, Jemal AA (2013) Analysis of fiducials implanted during EUS for patients with localized rectal cancer receiving high-dose rate endorectal brachytherapy
Nausea Rare, more commonly associated with oral dosing
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